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WISP2


Official Full Name
cellular communication network factor 5
Organism
Homo sapiens
Gene ID
8839
Background
This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover. [provided by RefSeq, Jul 2008]
Synonyms
CCN5; CT58; WISP2; CTGF-L

Cat.No. Product Name Price
SHG206385 shRNA set against Human WISP2(NM_003881.2) Inquiry
SHH447112 shRNA set against Mouse WISP2 (NM_016873.2) Inquiry
SHH447116 shRNA set against Rat WISP2 (NM_031590.1) Inquiry
SHW013731 shRNA set against Danio rerio WISP2 (NM_001199101) Inquiry
Cat.No. Product Name Price
CDCB175206 Danio rerio WISP2 ORF Clone (NM_001199101) Inquiry
CDCR051548 Human WISP2 ORF clone (NM_003881.2) Inquiry
CDCS411525 Human WISP2 ORF Clone (BC064379) Inquiry
CDFH021287 Human WISP2 cDNA Clone(NM_003881.2) Inquiry
CDFR012747 Rat Wisp2 cDNA Clone(NM_031590.1) Inquiry
MiUTR1H-11272 WISP2 miRNA 3'UTR clone Inquiry
MiUTR1R-08593 WISP2 miRNA 3'UTR clone Inquiry
CDCR379610 Rat Wisp2 ORF Clone(NM_031590.1) Inquiry
CDCS411526 Human WISP2 ORF Clone (BC017782) Inquiry
CDCS411527 Human WISP2 ORF Clone (BC058074) Inquiry
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