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VHL


Official Full Name
von Hippel-Lindau tumor suppressor
Organism
Homo sapiens
Gene ID
7428
Background
This gene encodes a component of a ubiquitination complex. The encoded protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. In addition to oxygen-related gene expression, this protein plays a role in many other cellular processes including cilia formation, cytokine signaling, regulation of senescence, and formation of the extracellular matrix. Variants of this gene are associated with von Hippel-Lindau syndrome, pheochromocytoma, erythrocytosis, renal cell carcinoma, and cerebellar hemangioblastoma. [provided by RefSeq, Jun 2022]
Synonyms
RCA1; VHL1; pVHL; HRCA1

Cat.No. Product Name Price
SHH442720 shRNA set against Mouse VHL (NM_009507.3) Inquiry
SHW011041 shRNA set against Danio rerio VHL (NM_001080684) Inquiry
SHH442716 shRNA set against Human VHL (NM_000551.3) Inquiry
SHH442724 shRNA set against Rat VHL (NM_052801.1) Inquiry
SHL125730 shRNA set against Rat Vhl(NM_052801.1) Inquiry
Cat.No. Product Name Price
CDFR013031 Rat Vhl cDNA Clone(NM_052801.1) Inquiry
MiUTR1M-12685 VHL miRNA 3'UTR clone Inquiry
MiUTR1R-08526 VHL miRNA 3'UTR clone Inquiry
MiUTR4H-TG09762 VHL miRNA 3'UTR clone Inquiry
CDCB172516 Danio rerio VHL ORF Clone (NM_001080684) Inquiry
CDCB187857 Rabbit VHL ORF clone (XM_008249986.1) Inquiry
CDCR380078 Rat Vhl ORF Clone(NM_052801.1) Inquiry
CDCS405737 Human VHL ORF Clone (BC058831) Inquiry
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