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REST


Official Full Name
RE1 silencing transcription factor
Organism
Homo sapiens
Gene ID
5978
Background
This gene was initially identified as a transcriptional repressor that represses neuronal genes in non-neuronal tissues. However, depending on the cellular context, this gene can act as either an oncogene or a tumor suppressor. The encoded protein is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regulator of neurogenesis. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2018]
Synonyms
WT6; XBR; HGF5; NRSF; DFNA27; GINGF5

Cat.No. Product Name Price
SHH392032 shRNA set against Human Rest (NM_005612.4) Inquiry
SHH392040 shRNA set against Rat Rest (NM_031788.1) Inquiry
SHH392036 shRNA set against Mouse Rest (NM_011263.2) Inquiry
Cat.No. Product Name Price
CDFL011414 Mouse Rest cDNA Clone(NM_011263.2) Inquiry
CDFR012920 Rat Rest cDNA Clone(NM_031788.1) Inquiry
MiUTR1H-08741 REST miRNA 3'UTR clone Inquiry
MiUTR1R-06379 REST miRNA 3'UTR clone Inquiry
SKO0740 REST Validated sgRNA vector Inquiry
CDCB192598 Rabbit REST ORF clone (XM_002717068.2) Inquiry
CDCR250378 Mouse Rest ORF Clone(NM_011263.2) Inquiry
CDCR379934 Rat Rest ORF Clone(NM_031788.1) Inquiry
CDCS409281 Human REST ORF Clone (BC132859) Inquiry
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