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RAB8A


Official Full Name
RAB8A, member RAS oncogene family
Organism
Homo sapiens
Gene ID
4218
Background
The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. [provided by RefSeq, Jul 2008]
Synonyms
MEL; RAB8

Cat.No. Product Name Price
SHH388600 shRNA set against Human RAB8A (NM_005370.4) Inquiry
SHH388604 shRNA set against Mouse RAB8A (NM_023126.2) Inquiry
SHH388608 shRNA set against Rat RAB8A (NM_053998.2) Inquiry
SHR160056 shRNA set against Mouse Rab8a(NM_023126.2) Inquiry
SHR160076 shRNA set against Human RAB8A(NM_005370.4) Inquiry
SHR160158 shRNA set against Rat Rab8a(NM_053998.2) Inquiry
SHW002092 shRNA set against Chicken RAB8A (NM_001031504) Inquiry
SHW011522 shRNA set against Danio rerio RAB8A (NM_001089562) Inquiry
Cat.No. Product Name Price
CDFH015762 Human RAB8A cDNA Clone(NM_005370.4) Inquiry
CDFH015763 Human RAB8A cDNA Clone(NM_005370.4) Inquiry
CDFR013700 Rat Rab8a cDNA Clone(NM_053998.2) Inquiry
MiUTR1H-08576 RAB8A miRNA 3'UTR clone Inquiry
MiUTR1M-09865 RAB8A miRNA 3'UTR clone Inquiry
MiUTR1R-06276 RAB8A miRNA 3'UTR clone Inquiry
SKO0735 RAB8A Validated sgRNA vector Inquiry
CDCB163567 Chicken RAB8A ORF Clone (NM_001031504) Inquiry
CDCB172997 Danio rerio RAB8A ORF Clone (NM_001089562) Inquiry
CDCB182214 Rabbit RAB8A ORF clone (XM_008249322.1) Inquiry
CDCH070922 Mouse Rab8a ORF clone (NM_023126.2) Inquiry
CDCH396204 Human RAB8A ORF clone(NM_005370.4) Inquiry
CDCR380733 Rat Rab8a ORF Clone(NM_053998.2) Inquiry
CDCS412224 Human RAB8A ORF Clone (BC002977) Inquiry
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