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METAP2


Official Full Name
methionyl aminopeptidase 2
Organism
Homo sapiens
Gene ID
10988
Background
The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Synonyms
MAP2; MNPEP; p67eIF2

Cat.No. Product Name Price
SHH185303 shRNA set against Rat Metap2(NM_022539.1) Inquiry
SHH185313 shRNA set against Mouse Metap2(NM_019648.3) Inquiry
SHH185339 shRNA set against Human METAP2(NM_006838.3) Inquiry
SHH340579 shRNA set against Human METAP2 (NM_006838.3) Inquiry
SHH340583 shRNA set against Mouse METAP2 (NM_019648.3) Inquiry
SHH340587 shRNA set against Rat METAP2 (NM_022539.1) Inquiry
SHW000322 shRNA set against Chicken METAP2 (NM_001006233) Inquiry
SHW015927 shRNA set against Danio rerio METAP2B (NM_199640) Inquiry
Cat.No. Product Name Price
CDFH011360 Human METAP2 cDNA Clone(NM_006838.3) Inquiry
CDFR012005 Rat Metap2 cDNA Clone(NM_022539.1) Inquiry
MiUTR1H-06215 METAP2 miRNA 3'UTR clone Inquiry
MiUTR1M-07058 METAP2 miRNA 3'UTR clone Inquiry
MiUTR1R-03764 METAP2 miRNA 3'UTR clone Inquiry
CDCB156059 Rat METAP2 ORF clone (BC091150.1) Inquiry
CDCB161797 Chicken METAP2 ORF Clone (NM_001006233) Inquiry
CDCB177402 Danio rerio METAP2B ORF Clone (NM_199640) Inquiry
CDCB183905 Rabbit METAP2 ORF clone (XM_008256902.1) Inquiry
CDCB195930 Rabbit LOC103351656 ORF clone (XM_008271888.1) Inquiry
CDCL185329 Human METAP2 ORF clone(NM_006838.3) Inquiry
CDCL185330 Mouse METAP2 ORF clone(NM_019648.3) Inquiry
CDCR379052 Rat Metap2 ORF Clone(NM_022539.1) Inquiry
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