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MAN1B1


Official Full Name
mannosidase alpha class 1B member 1
Organism
Homo sapiens
Gene ID
11253
Background
This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Dec 2011]
Synonyms
MRT15; ERMAN1; ERManI; MANA-ER

Cat.No. Product Name Price
SHH337275 shRNA set against Human MAN1B1 (NM_016219.4) Inquiry
SHH337279 shRNA set against Mouse MAN1B1 (NM_001029983.2) Inquiry
SHW011677 shRNA set against Danio rerio MAN1B1 (NM_001099979) Inquiry
Cat.No. Product Name Price
MiUTR3H-06729 MAN1B1 miRNA 3'UTR clone Inquiry
CDCB159158 Human MAN1B1 ORF clone (BC002953) Inquiry
CDCB173152 Danio rerio MAN1B1 ORF Clone (NM_001099979) Inquiry
CDCR231767 Mouse Man1b1 ORF Clone(NM_001029983.2) Inquiry
CDCS414216 Human MAN1B1 ORF Clone (BC002953) Inquiry
CDCS414217 Human MAN1B1 ORF Clone (BC006079) Inquiry
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