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IRF1


Official Full Name
interferon regulatory factor 1
Organism
Homo sapiens
Gene ID
3659
Background
The protein encoded by this gene is a transcriptional regulator and tumor suppressor, serving as an activator of genes involved in both innate and acquired immune responses. The encoded protein activates the transcription of genes involved in the body's response to viruses and bacteria, playing a role in cell proliferation, apoptosis, the immune response, and DNA damage response. This protein represses the transcription of several other genes. As a tumor suppressor, it both suppresses tumor cell growth and stimulates an immune response against tumor cells. Defects in this gene have been associated with gastric cancer, myelogenous leukemia, and lung cancer. [provided by RefSeq, Aug 2017]
Synonyms
MAR; IRF-1; IMD117

Cat.No. Product Name Price
SHH320557 shRNA set against Human IRF1 (NM_002198.2) Inquiry
SHH320561 shRNA set against Mouse IRF1 (NM_008390.2) Inquiry
SHH320565 shRNA set against Rat IRF1 (NM_012591.1) Inquiry
SHL173604 shRNA set against Rat Irf1(NM_012591.1) Inquiry
SHL173632 shRNA set against Mouse Irf1(NM_001159393.1) Inquiry
SHW005909 shRNA set against Chicken IRF1 (NM_205415) Inquiry
Cat.No. Product Name Price
CDFR010410 Rat Irf1 cDNA Clone(NM_012591.1) Inquiry
MiUTR1M-06095 IRF1 miRNA 3'UTR clone Inquiry
MiUTR1R-02690 IRF1 miRNA 3'UTR clone Inquiry
MiUTR4H-TG04570 IRF1 miRNA 3'UTR clone Inquiry
SKO0236 IRF1 Validated sgRNA vector Inquiry
CDCB167384 Chicken IRF1 ORF Clone (NM_205415) Inquiry
CDCB195134 Rabbit IRF1 ORF clone (XM_008254884.1) Inquiry
CDCH387269 Human IRF1 ORF clone(NM_002198.2) Inquiry
CDCL121563 Mouse Irf1 ORF clone (NM_001159393.1) Inquiry
CDCR238530 Mouse Irf1 ORF Clone(NM_001159396.1) Inquiry
CDCR245402 Mouse Irf1 ORF Clone(NM_008390.2) Inquiry
CDCR377457 Rat Irf1 ORF Clone(NM_012591.1) Inquiry
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