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INCENP


Official Full Name
inner centromere protein
Organism
Homo sapiens
Gene ID
3619
Background
In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA (centromere protein A; MIM 117139), CENPB (MIM 117140), CENPC1 (MIM 117141), and CENPD (MIM 117142). The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle (Earnshaw and Mackay, 1994 [PubMed 8088460]). These include CENPE (MIM 117143); MCAK (MIM 604538); KID (MIM 603213); cytoplasmic dynein (e.g., MIM 600112); CliPs (e.g., MIM 179838); and CENPF/mitosin (MIM 600236). The inner centromere proteins (INCENPs) (Earnshaw and Cooke, 1991 [PubMed 1860899]), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis (Cutts et al., 1999 [PubMed 10369859]).[supplied by OMIM, Mar 2008]
Synonyms
NESI; LMBD1; MAHCF; C6orf209

Cat.No. Product Name Price
SHH319449 shRNA set against Mouse INCENP (NM_016692.3) Inquiry
SHH319453 shRNA set against Rat INCENP (NM_001106335.1) Inquiry
SHL177342 shRNA set against Human INCENP(NM_020238.2) Inquiry
SHL177498 shRNA set against Human INCENP(NM_001040694.1) Inquiry
SHL177516 shRNA set against Human INCENP(NM_020238.2) Inquiry
SHW005825 shRNA set against Chicken INCENP (NM_205330) Inquiry
Cat.No. Product Name Price
CDFH009247 Human INCENP cDNA Clone(NM_001040694.1) Inquiry
CDFR006078 Rat Incenp cDNA Clone(NM_001106335.1) Inquiry
MiUTR1H-04942 INCENP miRNA 3'UTR clone Inquiry
MiUTR1H-04943 INCENP miRNA 3'UTR clone Inquiry
CDCB167300 Chicken INCENP ORF Clone (NM_205330) Inquiry
CDCB186791 Rabbit INCENP ORF clone (XM_008274397.1) Inquiry
CDCH387117 Mouse INCENP ORF clone(NM_016692.3) Inquiry
CDCL120899 Mouse INCENP ORF clone (NM_020238.2) Inquiry
CDCL120901 Mouse INCENP ORF clone (NM_001040694.1) Inquiry
CDCR373141 Rat Incenp ORF Clone(NM_001106335.1) Inquiry
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