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HP


Official Full Name
haptoglobin
Organism
Homo sapiens
Gene ID
3240
Background
This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. The protein encoded also exhibits antimicrobial activity against bacteria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
Synonyms
BP; HPA1S; HP2ALPHA2

Cat.No. Product Name Price
SHG196129 shRNA set against Human HEPH(NM_014799.2) Inquiry
SHH118289 shRNA set against Rat Heph(NM_133304.1) Inquiry
SHH130223 shRNA set against Human HPR(NM_020995.3) Inquiry
SHH303338 shRNA set against Mouse Gm3985 (NM_001177589.1) Inquiry
SHH311549 shRNA set against Human HEPH (NM_138737.3) Inquiry
SHH311553 shRNA set against Mouse HEPH (NM_181273.4) Inquiry
SHH311557 shRNA set against Rat HEPH (NM_133304.1) Inquiry
SHH314509 shRNA set against Human HP (NM_005143.3) Inquiry
SHH314513 shRNA set against Mouse HP (NM_017371.2) Inquiry
SHH314517 shRNA set against Rat HP (NM_053318.1) Inquiry
SHH314633 shRNA set against Mouse HPR (NM_013556.2) Inquiry
SHH314637 shRNA set against Rat HPR (NM_012583.2) Inquiry
SHH434248 shRNA set against Mouse Trf (NM_133977.2) Inquiry
Cat.No. Product Name Price
MiUTR3H-06679 DLC1 miRNA 3'UTR clone Inquiry
CDFG003130 Human HPR cDNA Clone(NM_020995.3) Inquiry
CDFG021241 Mouse Gm3985 cDNA Clone(NM_001177589.1) Inquiry
CDFG021649 Mouse Dlc1 cDNA Clone(NM_001194941.1) Inquiry
CDFH005132 Human DLC1 cDNA Clone(NM_001164271.1) Inquiry
CDFH008407 Human HEPH cDNA Clone(NM_014799.2) Inquiry
CDFH008741 Human HP cDNA Clone(NM_001126102.1) Inquiry
CDCR243336 Mouse Dlc1 ORF Clone(NM_001194940.2) Inquiry
CDFL005634 Mouse Heph cDNA Clone(NM_181273.4) Inquiry
CDFR010401 Rat Hp cDNA Clone(NM_012582.2) Inquiry
CDFR009537 Rat Dlc1 cDNA Clone(NM_001127446.1) Inquiry
MiUTR1H-04459 HEPH miRNA 3'UTR clone Inquiry
MiUTR1H-04686 HPR miRNA 3'UTR clone Inquiry
MiUTR1M-12109 TRF miRNA 3'UTR clone Inquiry
MiUTR1R-02415 HEPH miRNA 3'UTR clone Inquiry
MiUTR1R-02483 HP miRNA 3'UTR clone Inquiry
MiUTR3H-00992 HP miRNA 3'UTR clone Inquiry
MiUTR3H-00993 HP miRNA 3'UTR clone Inquiry
MiUTR3H-02609 HEPH miRNA 3'UTR clone Inquiry
CDFR013977 Rat Heph cDNA Clone(NM_133304.1) Inquiry
MiUTR3H-02611 HEPH miRNA 3'UTR clone Inquiry
CDCS407747 Human HP ORF Clone (BC121125) Inquiry
CDCS408743 Human DLC1 ORF Clone (BC049842) Inquiry
CDCS407958 Human HEPH ORF Clone (BC011561) Inquiry
CDCR381011 Rat Heph ORF Clone(NM_133304.1) Inquiry
CDCR377448 Rat Hp ORF Clone(NM_012582.2) Inquiry
CDCB180509 Rabbit HP ORF clone (NM_001082110.1) Inquiry
CDCB182356 Rabbit HEPH ORF clone (XM_008272725.1) Inquiry
CDCB186358 Rabbit DLC1 ORF clone (XM_008274056.1) Inquiry
CDCL118261 Human HPR ORF clone (NM_020995.3) Inquiry
CDCL150944 Human Gm3985 ORF clone (NM_001177589.1) Inquiry
CDCL186621 Mouse TRF ORF clone(NM_133977.2) Inquiry
CDCR050104 Mouse Heph ORF clone (NM_001159628.1) Inquiry
CDCR050106 Mouse Heph ORF clone (NM_001159627.1) Inquiry
CDCR050112 Human HEPH ORF clone (NM_138737.3) Inquiry
CDCS407746 Human HP ORF Clone (BC058031) Inquiry
CDCR050114 Human HEPH ORF clone (NM_014799.2) Inquiry
CDCR055810 Human DLC1 ORF clone (NM_001164271.1) Inquiry
CDCR243338 Mouse Dlc1 ORF Clone(NM_001194941.1) Inquiry
CDCR248959 Mouse Heph ORF Clone(NM_010417.2) Inquiry
CDCR252527 Mouse Dlc1 ORF Clone(NM_015802.3) Inquiry
CDCR253211 Mouse Hp ORF Clone(NM_017370.2) Inquiry
CDCR275463 Mouse Heph ORF Clone(NM_181273.4) Inquiry
CDCR348451 Human HP ORF Clone(NM_001126102.1) Inquiry
CDCR349690 Human HEPH ORF Clone(NM_001130860.2) Inquiry
CDCR376578 Rat Dlc1 ORF Clone(NM_001127446.1) Inquiry
CDCR055804 Human DLC1 ORF clone (NM_182643.2) Inquiry
CDCB159696 Human HP ORF clone (BC058031) Inquiry
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