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DPM1


Official Full Name
dolichyl-phosphate mannosyltransferase subunit 1, catalytic
Organism
Homo sapiens
Gene ID
8813
Background
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
Synonyms
MPDS; CDGIE

Cat.No. Product Name Price
SHG209035 shRNA set against Human DPM1(NM_003859.1) Inquiry
SHG209053 shRNA set against Mouse Dpm1(NM_010072.3) Inquiry
SHH280605 shRNA set against Human DPM1 (NM_003859.1) Inquiry
SHH280609 shRNA set against Mouse DPM1 (NM_010072.3) Inquiry
SHH280613 shRNA set against Rat DPM1 (NM_001106544.1) Inquiry
SHW006909 shRNA set against Danio rerio DPM1 (NM_001003596) Inquiry
Cat.No. Product Name Price
CDCS411512 Human DPM1 ORF Clone (BC007073) Inquiry
CDFH005386 Human DPM1 cDNA Clone(NM_003859.1) Inquiry
CDFR005711 Rat Dpm1 cDNA Clone(NM_001106544.1) Inquiry
MiUTR1H-02970 DPM1 miRNA 3'UTR clone Inquiry
MiUTR1M-03983 DPM1 miRNA 3'UTR clone Inquiry
CDCB158894 Human DPM1 ORF clone (BC007073) Inquiry
CDCB168384 Danio rerio DPM1 ORF Clone (NM_001003596) Inquiry
CDCB185326 Rabbit DPM1 ORF clone (XM_008250430.1) Inquiry
CDCR057076 Human DPM1 ORF clone (NM_003859.1) Inquiry
CDCR057078 Mouse Dpm1 ORF clone (NM_010072.3) Inquiry
CDCR373328 Rat Dpm1 ORF Clone(NM_001106544.1) Inquiry
CDCS411511 Human DPM1 ORF Clone (BC008466) Inquiry
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