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CD4


Official Full Name
CD4 molecule
Organism
Homo sapiens
Gene ID
920
Background
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
Synonyms
T4; IMD79; Leu-3; OKT4D; CD4mut

Cat.No. Product Name Price
SHG157393 shRNA set against Rat Cd4(NM_012705.1) Inquiry
SHG157411 shRNA set against Mouse Cd4(NM_013488.2) Inquiry
SHH259093 shRNA set against Human CD4 (NM_000616.4) Inquiry
SHH259097 shRNA set against Mouse CD4 (NM_013488.2) Inquiry
SHH259101 shRNA set against Rat CD4 (NM_012705.1) Inquiry
SHW005160 shRNA set against Chicken CD4 (NM_204649) Inquiry
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OE-PNDC000051 Human CD4 Nanodisc Inquiry
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CDCB156741 Ferret CD4 ORF clone (EF492055.1) Inquiry
CDCL183333 Mouse CD4 ORF clone(NM_013488.2) Inquiry
CDFR010519 Rat Cd4 cDNA Clone(NM_012705.1) Inquiry
MiUTR1M-02769 CD4 miRNA 3'UTR clone Inquiry
MiUTR1R-00846 CD4 miRNA 3'UTR clone Inquiry
MiUTR3H-02185 CD4 miRNA 3'UTR clone Inquiry
CDCB156557 Cynomolgus CD4 ORF clone Inquiry
CDCB166635 Chicken CD4 ORF Clone (NM_204649) Inquiry
CDCB174539 Danio rerio CD4 ORF Clone (NM_001135096) Inquiry
CDCB180778 Rabbit CD4 ORF clone (NM_001082313.2) Inquiry
CDCL183334 Mouse CD4 ORF clone(NM_012705.1) Inquiry
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CC-281 CD4 Easy KO Kit Inquiry
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