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ADRA1A


Official Full Name
adrenoceptor alpha 1A
Organism
Homo sapiens
Gene ID
148
Background
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]
Synonyms
ADRA1C; ADRA1L1; ALPHA1AAR

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OE-PNDC000739 Human ADRA1A Nanodisc Inquiry
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