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AANAT


Official Full Name
aralkylamine N-acetyltransferase
Organism
Homo sapiens
Gene ID
15
Background
The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Synonyms
MCAF2

Cat.No. Product Name Price
AD00423Z Human AANAT adenoviral particles Inquiry
Cat.No. Product Name Price
SHH228630 shRNA set against Mouse AANAT (NM_009591.3) Inquiry
SHG022015 shRNA set against Rat Aanat(NM_012818.2) Inquiry
SHH228626 shRNA set against Human AANAT (NM_001088.2) Inquiry
SHH228634 shRNA set against Rat AANAT (NM_012818.2) Inquiry
SHW005657 shRNA set against Chicken AANAT (NM_205158) Inquiry
Cat.No. Product Name Price
CDCR022684 Human AANAT ORF clone (NM_001166579.1) Inquiry
CDCR247517 Mouse Aanat ORF Clone(NM_009591.3) Inquiry
CDFH000017 Human AANAT cDNA Clone(NM_001166579.1) Inquiry
CDFR010675 Rat Aanat cDNA Clone(NM_012818.2) Inquiry
MiUTR1R-00010 AANAT miRNA 3'UTR clone Inquiry
MiUTR4H-TG00011 AANAT miRNA 3'UTR clone Inquiry
CDCB167132 Chicken AANAT ORF Clone (NM_205158) Inquiry
CDCB183385 Rabbit AANAT ORF clone (XM_008250906.1) Inquiry
CDCR377678 Rat Aanat ORF Clone(NM_012818.2) Inquiry
CDCS407386 Human AANAT ORF Clone (BC069434) Inquiry
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