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MicroRNA Agomir/ Antagomir Synthesis Service

email info@www.creative-biogene.com Tel: 1-631-626-9181 Fax: 1-631-614-7828
Creative Biogene is a global leading agomir/ antagomir service provider for all passionate scientific researchers and our comprehensive synthesis service is supported by Cutting-Edge Chemical Synthesis Technology.

Agomir/antagomir are members of a novel class of chemically engineered oligonucleotides. Agomir is chemically-modified double-strand miRNA mimics which can mimic mature endogenous miRNAs after transfection into cells. The antisense strand has 2 phosphorothioates at the 5' end, 4 phosphorothioates, 4 cholesterol groups at the 3' end, and full length nucleotide 2'-methoxy modification. Antagomir is single-strand miRNA inhibitor carrying the same modifications functioning by blocking miRNA regulation of target gene expression efficiently.

Creative Biogene provides agomir/ antagomir synthesis service that covers all human, mouse and rat miRNAs in the current miRBase. Our MicroRNA agomir/ antagomir synthesis service provides unparalleled advantages:
  1. Cover all human, mouse and rat miRNAs listed in miRBase
  2. More stable and easy to transfect due to modifications
  3. Purified and ready-to transfect
  4. Cost effective and fast turnaround time

(Fig. a) It shows the interfering effect of antagomir miRNA is much better than other chemical modified miRNA.

(Fig. b) Antagomir can inhibit the target microRNA specifically. The effects of antagomir -122 were found to be specific because a control for antagomir -122 that harbored four mismatch mutations (mm- antagomir-122) had no effect on miR-122 levels. Furthermore, expression levels of let7 and miR-22 were unaffected treated with antagomir-122 and mm-antagomir-122, indicating that silencing was miRNA-specific.

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45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email:info@creative-biogene.com
Europe
Tel: 44-207-048-3343

Email:info@creative-biogene.com
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CONTACT CREATIVE BIOGENE

45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-048-3343

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