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Gene Knockout Stable Cell Lines

email info@creative-biogene.com Tel: 1-631-626-9181 Fax: 1-631-614-7828

Gene Knockout Stable Cell Lines

Our scientists have years of experience at performing gene editing with CRISPR/Cas9, from designing gRNA to transfection and single clone generation. Creative Biogene is offering a series of gene knockout cell lines developed by CRISPR/Cas9 system. These cell lines provide you with a convenient means to study gene functions.

The CRISPR/Cas9 system is an adaptive immunity system in bacteria against bacteriophage invading. It has been developed as the most popular method for genome editing in recent years. The engineered CRISPR/Cas9 technology consists of a single guide RNA (sgRNA) and a human codon-optimized Cas9 nuclease. The sgRNA recognizes the genomic target via standard Watson–crick base pairing and acts as a scaffold for binding of the endonuclease Cas9. Then Cas9 protein introduces site-specific DSBs in the target DNA sequences. Besides, in the phase of target recognition, the protospacer-adjacent motif (PAM) adjacent to the 3’ end of the DNA target site is indispensable. Finally, targeted mutations can be induced by nonhomologous end joining (NHEJ).

Applications
• Studying gene functions
• Designing disease models
• Applied in biopharmaceutical research
• Screening drugs

Advantages
One-stop service: Customized cell generation project was managed by experienced scientists throughout the process, from construction design to drug screening.
Experienced: Creative Biogene has professional research team with experience of many years in the field of molecular and cell biology.
Genetic stability: Our knockout stable cell lines has been rigorously tested and validated. The target gene can be stably inherited for more than 25 generations.
High Quality: Our knockout stable cell lines have no mycoplasma contamination.

  Order Info:Gene Knockout Stable Cell Lines  order info
Contact us to order
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email:info@creative-biogene.com
Europe
Tel: 44-207-048-3343

Email:info@creative-biogene.com
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CONTACT US TO ORDER


CONTACT CREATIVE BIOGENE

45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-048-3343

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